BeNano series

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The BeNano series for nanoparticle analysis

Particle characterization from 0.3 nm to 15 µm in terms of size, molecular weight and zeta potential using DLS, SLS and ELS

The BeNano series is the latest generation of nanoparticle size and zeta potential measuring devices. This system combines dynamic light scattering (DLS), electrophoretic light scattering (ELS) and static light scattering (SLS) to provide accurate measurements of particle size, zeta potential and molecular weight. The BeNano series is widely used in both academic and industrial applications in various industries, especially in biotechnology and life science, pharmaceutical, food and chemical industries.

Your benefits:

  • Particle size measurement from 0.3 nm – 15 µm with DLS from 3 µl sample volume

  • Zeta potential determination with ELS/ PALS

  • Molecular weight measurement with SLS

  • Microrheology properties with µDLS

  • Perfect price-performance ratio

  • Dynamic light scattering (DLS) with advanced backscatter signal detection (173°, variable measuring zone) for highly sensitive particle size measurements and variable concentration range
  • Disposable capillary cell for particle size determination of very small sample volumes (up to 3 µl) and higher measurement accuracy for coarser particles
  • Electrophoretic light scattering (ELS) with innovative PALS technology for precise zeta potential measurements even in organic solvents or highly conductive systems
  • Flexible 3-syringe auto-titrator BAT-1 for precise, automatic pH-dependent investigations
  • Microrheological investigations using dynamic light scattering technology (µDLS)
  • Temperature trend experiments in a wide temperature range (-10 – 110°C)
  • Intuitive, SOP-based software for fast and precise measurements and intelligent evaluation of scattered light signals for accurate and stable results
  • Compliance with 21 CFR Part 11, ISO 22412, ISO 13099

Autotitrator BAT-1

The autotitrator BAT-1 is compatible with the BeNano series and is an ideal option for the automatic determination of the zeta potential of a sample in dependence of the pH value as well as the determination of the isoelectric point (IEP). It is equipped with three high-precision titration pumps with an accuracy of 0.28 μL. The appropriate titrant is automatically selected by the system and the addition volume is continuously adjusted using an intelligent routine.

  • SOP-controlled pH titration with three high-precision titration pumps
  • Automatic determination of the isoelectric point (IEP)
  • Automatic selection of the appropriate titrant with continuous adjustment of the addition volume
  • Integrated magnetic stirrer system, corrosion-resistant circulation system suitable for very low pH values

 

DLS-Flowmode Option

The DLS Flowmode Option is a special setup for the DLS versions of the BeNano series to measure the particle sizes of individual fractions in high resolution in conjunction with connected separation process equipment (e.g. GPC, FFF). The option is available either only as a flow cell for recording the intensity distribution or additionally with a BFC signal collector for simultaneous recording of the RI or UV curve and thus direct measurement of the volume and/or number distribution curve.

  • Particle size measurement of individual size fractions in high resolution using DLS in conjunction with a connected separation process (GPC, FFF)
  • Measurement of the intensity distribution, optionally the volume or number distribution via RI/UV curve recording

 

Measurement cells/ cuvettes

Particle size measurement

PS Cuvette
Aqueous systems
Material: Polystyrol (PS)
Sample volume: 1 – 1,5 ml
Temperature range: -15 – 70°C
Glass Cuvette
Aqueous and organic systems
Material: Quartz glass
Sample volume:  1 – 1,5 ml
Temperature range: -15 – 110°C
Capillary Sizing Cell
Aqueous and organic systems
Smallest volume
Material: Quartz glass
Sample volume:  3-5 µl
Temperature range: -15 – 70°C
Micro-volume Cuvette
Aqueous systems, small volume
Material: Polymethyl methacrylate (PMMA)
Sample volume: 40-50 µl
Temperature range: -15 – 70°C
Micro-volume Glass Cuvette
Aqueous systems, small volume
Material: Quartz glass
Sample volume: 25 µl
Temperature range: -15 – 110°C
Flow Cell
Aqueous and organic systems, DLS Flow mode
Material: Quartz glass
Sample volume: 27 µl
Temperature range: 0 – 70°C
Micro-volume Fluorescence-filtered Cell
Aqueous systems
Material: Quartz glass
Sample volume: 16 µl
Temperature range: 0 – 90°C
Measurement Angle: 90°, 173
Micro-volume VH Cell
Aqueous systems
Eliminating the vertical element of scattered light
Material: Quartz glass
Sample volume: 16 µl
Temperature range: 0 – 90°C
Measurement Angle: 90°
Micro-volume VV Cell
Aqueous systems
Eliminating the horizontal element of scattered light
Material: Quartz glass
Sample volume: 16 µl
Temperature range: 0 – 90°C
Measurement Angle: 90°, 173°
 

Zeta potential measurement

Folded Capillary Cell BT-C1
Aqueous systems
Material: Polycarbonate (PC)
Electrodes: Gold-plated Phosphor Bronze,
Sample volume: 0,75 ml
Temperature range: -15 – 70°C
Dip Cell
Aqueous and organic systems
Material: Polyether ether ketones (PEEK)
Sample volume: 1 – 1,5 ml
Temperature range: -15 – 70°C
Folded Capillary Cell BT-C1-Pt
Aqueous systems (corrosive)
Material: Polycarbonate (PC)
Electrodes: Platinum
Sample volume: 0,75 ml
Temperature range: -15 – 70°C

Norms

/1/ ISO 22412:2017 Particle size analysis — Dynamic light scattering (DLS)
/2/ ISO 13099-2 Colloidal systems – Methods for zeta-potential determination – Part 2: Optical methods

Technical articles

/2/ CIT (Chemie Ingenieur Technik) 03/2022; „Nanomaterialidentifikation entsprechend EU-Definition“ [German only]
/3/ CIT (Chemie Ingenieur Technik) 01-02/2023; „Partikelgrößen- und Zetapotentialmessung an verdünnten und original konzentrierten Nano-Oxidsuspensionen“ [German only]

Application Notes upon request







     

     
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    Biochemistry-Biotechnology: blood, vaccines, proteins

    Blood tests

    Vaccines

    Proteins

    Paints-Coatings

    Inks, Color pigments

    Paints

    Nanomaterials

    MOFs

    Colloidal Systems

    Pharmaceuticals: API development, formulations

    LNP-transport molecules

    Pharmaceutical formulations

    Food

    Food additives

    Beverage analysis

    Dairy product testing

    Specifications

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    Contact

    Service hotline (Germany)
    +49 8134 9324 0

    Contact us via Email
    info@3P-instruments.com